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Operations research is an interdisciplinary science that develops scientific methods for modeling and solving decision problems. Software tools are essential in practicing OR, because model formulations and solution techniques are complex and require the use of computers. So, there are well-established software frameworks and implementations to support OR methodologies. Python, a dynamically typed language, can implement these software frameworks for major OR methodologies (mathematical programming and simulation) in the same programming environment. By doing so, Python, in effect, glues software environments that have been independent, thus improving the software development cycle for sophisticated applications requiring different model types. This article is part of a special issue on dynamically typed languages.