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This paper proposes a framework for agent-based distributed machine learning and data mining based on (i) the exchange of meta-level descriptions of individual learning processes among agents and (ii) online reasoning about learning success and learning progress by learning agents. We present an abstract architecture that enables agents to exchange models of their local learning processes and introduces a number of different methods for integrating these processes. This allows us to apply existing agent interaction mechanisms to distributed machine learning tasks, thus leveraging the powerful coordination methods available in agent-based computing, and enables agents to engage in meta-reasoning about their own learning decisions. We apply this architecture to a real-world distributed clustering application to illustrate how the conceptual framework can be used in practical systems in which different learners may be using different datasets, hypotheses and learning algorithms. We report on experimental results obtained using this system, review related work on the subject, and discuss potential future extensions to the framework.