Overview and utilization of the NCI Thesaurus: Conference Papers
Comparative and Functional Genomics
Modeling a description logic vocabulary for cancer research
Journal of Biomedical Informatics
NCI Thesaurus: A semantic model integrating cancer-related clinical and molecular information
Journal of Biomedical Informatics
Ontologies and Data Integration in Biomedicine: Success Stories and Challenging Issues
DILS '08 Proceedings of the 5th international workshop on Data Integration in the Life Sciences
Translational integrity and continuity: Personalized biomedical data integration
Journal of Biomedical Informatics
Semantic technologies in electronic government
Proceedings of the 2nd international conference on Theory and practice of electronic governance
The NCI Thesaurus quality assurance life cycle
Journal of Biomedical Informatics
The caBIG terminology review process
Journal of Biomedical Informatics
Integration of prostate cancer clinical data using an ontology
Journal of Biomedical Informatics
Federated querying architecture for clinical & translational health IT
Proceedings of the 1st ACM International Health Informatics Symposium
Discovering evolving regions in life science ontologies
DILS'10 Proceedings of the 7th international conference on Data integration in the life sciences
Journal of Biomedical Informatics
DW4TR: A Data Warehouse for Translational Research
Journal of Biomedical Informatics
Federated Querying Architecture with Clinical & Translational Health IT Application
Journal of Medical Systems
Quality evaluation of cancer study Common Data Elements using the UMLS Semantic Network
Journal of Biomedical Informatics
Towards collaborative data management in the VPH-Share project
Euro-Par'11 Proceedings of the 2011 international conference on Parallel Processing
Clinical data interoperability based on archetype transformation
Journal of Biomedical Informatics
Journal of Biomedical Informatics
Journal of Biomedical Informatics
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One of the requirements for a federated information system is interoperability, the ability of one computer system to access and use the resources of another system. This feature is particularly important in biomedical research systems, which need to coordinate a variety of disparate types of data. In order to meet this need, the National Cancer Institute Center for Bioinformatics (NCICB) has created the cancer Common Ontologic Representation Environment (caCORE), an interoperability infrastructure based on Model Driven Architecture. The caCORE infrastructure provides a mechanism to create interoperable biomedical information systems. Systems built using the caCORE paradigm address both aspects of interoperability: the ability to access data (syntactic interoperability) and understand the data once retrieved (semantic interoperability). This infrastructure consists of an integrated set of three major components: a controlled terminology service (Enterprise Vocabulary Services), a standards-based metadata repository (the cancer Data Standards Repository) and an information system with an Application Programming Interface (API) based on Domain Model Driven Architecture. This infrastructure is being leveraged to create a Semantic Service-Oriented Architecture (SSOA) for cancer research by the National Cancer Institute's cancer Biomedical Informatics Grid (caBIG(TM)).