NetworkBLAST

  • Authors:
  • Maxim Kalaev;Mike Smoot;Trey Ideker;Roded Sharan

  • Affiliations:
  • -;-;-;-

  • Venue:
  • Bioinformatics
  • Year:
  • 2008

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Abstract

Summary: The identification of protein complexes is a fundamental challenge in interpreting protein–protein interaction data. Cross-species analysis allows coping with the high levels of noise that are typical to these data. The NetworkBLAST web-server provides a platform for identifying protein complexes in protein-protein interaction networks. It can analyze a single network or two networks from different species. In the latter case, NetworkBLAST outputs a set of putative complexes that are evolutionarily conserved across the two networks. Availability: NetworkBLAST is available as web-server at: www.cs.tau.ac.il/~roded/networkblast.htm Contact:kalaevma@post.tau.ac.il; roded@post.tau.ac.il