Targeted strategies for tuberculosis in areas of high HIV prevalence: a simulation study

Authors:
Georgina R. Mellor;Christine S. M. Currie;Elizabeth L. Corbett;Russell C. H. Cheng
Affiliations:
University of Southampton, Highfield, Southampton, U.K.;University of Southampton, Highfield, Southampton, U.K.;London School of Hygiene and Tropical Medicine, Harare, Zimbabwe;University of Southampton, Highfield, Southampton, U.K.
Venue:
Proceedings of the 39th conference on Winter simulation: 40 years! The best is yet to come
Year:
2007

Citing 2
Cited 0

Verification and validation of simulation models

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Modeling tuberculosis in areas of high HIV prevalence

Proceedings of the 38th conference on Winter simulation

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Abstract

We describe the analysis of a discrete event simulation model of tuberculosis (TB) and HIV disease, parameterized to describe the dual epidemics in Harare, Zimbabwe. The HIV epidemic in Sub-Saharan Africa is particularly severe and has led to a significant rise in TB cases. We use the model to evaluate new strategies for improved detection of TB cases in a high HIV prevalence setting. The structure of the model and its validation will be discussed, but the paper will focus on the analysis of the model output.