On stent-graft models in thoracic aortic endovascular repair: A computational investigation of the hemodynamic factors

  • Authors:
  • George S. K. Fung;S. K. Lam;Stephen W. K. Cheng;K. W. Chow

  • Affiliations:
  • Department of Electrical and Electronic Engineering, University of Hong Kong, Pokfulam Road, Hong Kong;Department of Mechanical Engineering, University of Hong Kong, Pokfulam Road, Hong Kong;Division of Vascular Surgery, Department of Surgery, University of Hong Kong, Pokfulam Road, Hong Kong;Department of Mechanical Engineering, University of Hong Kong, Pokfulam Road, Hong Kong

  • Venue:
  • Computers in Biology and Medicine
  • Year:
  • 2008

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Abstract

In treating thoracic aortic diseases, endovascular repair involves the placement of a self-expanding stent-graft system across the diseased thoracic aorta. Computational fluid dynamic techniques are applied to model the blood flow by numerically solving the three-dimensional continuity equation and the time-dependent Navier-Stokes equations for an incompressible fluid. From our results, high blood pressure level and high systolic slope of the pressure waveform will significantly increase the drag force on a stent-graft whereas high blood viscosity causes only a mild increase. It indicates that hemodynamic factors might have an important impact on the drag force and thus play a significant role in the risk of stent-graft failure.