Biomolecular autonomous solution of the Hamiltonian path problem via hairpin formation

  • Authors:
  • Israel M. Martinez-Perez;Gong Zhang;Zoya Ignatova;Karl-Heinz Zimmermann

  • Affiliations:
  • Department of Computer Engineering, Hamburg University of Technology, 21071 Hamburg, Germany.;Biotechnology II, Hamburg University of Technology, 21071 Hamburg, Germany.;Biotechnology II, Hamburg University of Technology, 21071 Hamburg, Germany;Department of Computer Engineering, Hamburg University of Technology, 21071 Hamburg, Germany

  • Venue:
  • International Journal of Bioinformatics Research and Applications
  • Year:
  • 2005

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Abstract

The Hamiltonian path problem is one of the famous hard combinatorial problems. We provide the first molecular-scale autonomous solution of the decision Hamiltonian path problem. It is based on the formation of secondary structures of DNA molecules.