Rotational and translational alignment errors in 3D reconstruction of virus structures at high resolution

Authors:
Yongchang Ji;Dan C. Marinescu
Affiliations:
School of Electrical Engineering and Computer Science, University of Central Florida, Orlando, FL 32816, USA.;School of Electrical Engineering and Computer Science, University of Central Florida, Orlando, FL 32816, USA
Venue:
International Journal of Bioinformatics Research and Applications
Year:
2006

Citing 3
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Abstract

The 3D reconstruction of virus structures at high resolution using CryoTEM data requires a very accurate rotational and translational alignment of individual views obtained experimentally. We discuss the geometrical foundations and the computational problems raised by rotational and translational alignment. We also outline the basic ideas for CTF correction.