MESSM: a framework for protein fold recognition using Neural Networks and Support Vector Machines

  • Authors:
  • Nan Jiang;Wendy Wu;Ian Mitchell

  • Affiliations:
  • School of Computing Science, Middlesex University, London EN4 4BT, UK.;School of Computing Science, Middlesex University, London EN4 4BT, UK.;School of Computing Science, Middlesex University, London EN4 4BT, UK

  • Venue:
  • International Journal of Bioinformatics Research and Applications
  • Year:
  • 2006

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Abstract

A new framework (called MESSM) for protein fold recognition with three key features is proposed in this paper. Being tested on three benchmark problems, the results show that the MESSM has a comparable performance on fold recognition to those more computational intensive, energy potential based fold recognition models. The MESSM leads to a better performance on alignment accuracy. The MESSM presents a new way to develop an efficient tool for protein fold recognition.