Optimizing synaptic conductance calculation for network simulations

  • Authors:
  • William W. Lytton

  • Affiliations:
  • Department of Neurology, University of Wisconsin, Wm. S. Middleton VA Hospital, 1300 University Ave., MSC 1720, Madison, WI 53706 USA

  • Venue:
  • Neural Computation
  • Year:
  • 1996

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Abstract

High computational requirements in realistic neuronal network simulations have led to attempts to realize implementation efficiencies while maintaining as much realism as possible. Since the number of synapses in a network will generally far exceed the number of neurons, simulation of synaptic activation may be a large proportion of total processing time. We present a consolidating algorithm based on a recent biophysically-inspired simplified Markov model of the synapse. Use of a single lumped state variable to represent a large number of converging synaptic inputs results in substantial speed-ups.