Dissociating Task-set Selection from Task-set Inhibition in the Prefrontal Cortex
Journal of Cognitive Neuroscience
Decomposing Components of Task Preparation with Functional Magnetic Resonance Imaging
Journal of Cognitive Neuroscience
Journal of Cognitive Neuroscience
Contributions of the Prefrontal Cortex and Basal Ganglia to Set Shifting
Journal of Cognitive Neuroscience
Toward a Functional Analysis of the Basal Ganglia
Journal of Cognitive Neuroscience
The Human Striatum is Necessary for Responding to Changes in Stimulus Relevance
Journal of Cognitive Neuroscience
Executive control of retrieval in noun and verb generation
Cognitive Systems Research
Hi-index | 0.00 |
The performance of patients with lesions involving the basal ganglia (BG) was compared to that of patients with prefrontal (PFC) lesions, thalamic (TH) lesions, and age-matched controls in order to examine the specific role of the BG within the frontal-subcortical circuits (FSCC) in task switching. All the BG patients and none of the other participants showed a marked increase in error rate in incongruent trials where correct responses depended upon the choice of the correct task rule. Some BG patients erred in failing to switch tasks and others failed despite their attempt to switch tasks. Additionally, reaction time results indicate abnormal response repetition effects among the BG patients; failure in benefiting from advance task information among all the patients; and increased task mixing costs following PFC lesions. The authors conclude that although the frontal-subcortical circuits jointly determine some behaviors (such as benefiting from preparation), the BG play a unique role within the FSCC in action selection and/or the inhibition of irrelevant information.