Journal of Biomedical Informatics
Gaussian mixture decomposition in the analysis of MALDI-TOF spectra
Expert Systems: The Journal of Knowledge Engineering
| Hi-index | 3.84 |
Summary: The knowledge base EPO-KB (Empirical Proteomic Ontology Knowledge Base) is based on an OWL ontology that represents current knowledge linking mass-to-charge (m/z) ratios to proteins on multiple platforms including Matrix Assisted Laser/Desorption Ionization (MALDI) and Surface Enhanced Laser/Desorption Ionization (SELDI) – Time of Flight (TOF). At present, it contains information on m/z ratio to protein links that were extracted from 120 published research papers. It has a web interface that allows researchers to query and retrieve putative proteins that correspond to a user-specified m/z ratio. EPO-KB also allows automated entry of additional m/z ratio to protein links and is expandable to the addition of gene to protein and protein to disease links. Availability: http://www.dbmi.pitt.edu/EPO-KB Contact: JLL47@pitt.edu