Identification of the optic nerve head with genetic algorithms

  • Authors:
  • Enrique J. Carmona;Mariano Rincón;Julián García-Feijoó;José M. Martínez-de-la-Casa

  • Affiliations:
  • Departamento de Inteligencia Artificial, Escuela Técnica Superior de Ingeniería Informática, Universidad Nacional de Educación a Distancia, C/Juan del Rosal 16, 28040 Madrid, S ...;Departamento de Inteligencia Artificial, Escuela Técnica Superior de Ingeniería Informática, Universidad Nacional de Educación a Distancia, C/Juan del Rosal 16, 28040 Madrid, S ...;Departamento de Glaucoma, Servicio de Oftalmología, Hospital Clínico San Carlos, Instituto de Investigaciones Ramón Castroviejo, Universidad Complutense, Madrid, Spain;Departamento de Glaucoma, Servicio de Oftalmología, Hospital Clínico San Carlos, Instituto de Investigaciones Ramón Castroviejo, Universidad Complutense, Madrid, Spain

  • Venue:
  • Artificial Intelligence in Medicine
  • Year:
  • 2008

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Abstract

Objective: This work proposes creating an automatic system to locate and segment the optic nerve head (ONH) in eye fundus photographic images using genetic algorithms. Methods and material: Domain knowledge is used to create a set of heuristics that guide the various steps involved in the process. Initially, using an eye fundus colour image as input, a set of hypothesis points was obtained that exhibited geometric properties and intensity levels similar to the ONH contour pixels. Next, a genetic algorithm was used to find an ellipse containing the maximum number of hypothesis points in an offset of its perimeter, considering some constraints. The ellipse thus obtained is the approximation to the ONH. The segmentation method is tested in a sample of 110 eye fundus images, belonging to 55 patients with glaucoma (23.1%) and eye hypertension (76.9%) and random selected from an eye fundus image base belonging to the Ophthalmology Service at Miguel Servet Hospital, Saragossa (Spain). Results and conclusions: The results obtained are competitive with those in the literature. The method's generalization capability is reinforced when it is applied to a different image base from the one used in our study and a discrepancy curve is obtained very similar to the one obtained in our image base. In addition, the robustness of the method proposed can be seen in the high percentage of images obtained with a discrepancy @d