Engineering aspects of the osteoarticular reconstruction with stem cells: study on animals

  • Authors:

  • Mircea Dreucean;Mirela Toth-Tascau;Lucian Rusu;Dan Ioan Stoia;Karoly Menyhardt

  • Affiliations:

  • Politehnica University of Timisoara, Faculty of Mechanical Engineering, CMPICSU Research Group, Timisoara, Romania;Politehnica University of Timisoara, Faculty of Mechanical Engineering, CMPICSU Research Group, Timisoara, Romania;Politehnica University of Timisoara, Faculty of Mechanical Engineering, CMPICSU Research Group, Timisoara, Romania;Politehnica University of Timisoara, Faculty of Mechanical Engineering, CMPICSU Research Group, Timisoara, Romania;Politehnica University of Timisoara, Faculty of Mechanical Engineering, CMPICSU Research Group, Timisoara, Romania

  • Venue:
  • MCBC'08 Proceedings of the 9th WSEAS International Conference on Mathematics & Computers In Biology & Chemistry
  • Year:
  • 2008

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Abstract

For a great number of medical applications the STEM cells offer new possibilities of healing and recovery. The present study uses a number of dogs and rabbits with induced defects at the femoris condylis on the purpose of being implanted with STEM cells in the side area of the knee articulation. The 3D reconstruction of the defect area based on CT scans is presented in the paper. The process of customization and the particular implant shape for each subject are also presented in the paper. The scaffold implanted in the defect area was designed in a CAD environment and fixed on the femur of the animal with HDPE screws or Polycaprolactone nails.