The AppLeS parameter sweep template: user-level middleware for the grid
Proceedings of the 2000 ACM/IEEE conference on Supercomputing
High Performance Parametric Modeling with Nimrod/G: Killer Application for the Global Grid?
IPDPS '00 Proceedings of the 14th International Symposium on Parallel and Distributed Processing
CBMS '05 Proceedings of the 18th IEEE Symposium on Computer-Based Medical Systems
The Anatomy of the Grid: Enabling Scalable Virtual Organizations
International Journal of High Performance Computing Applications
A portal for grid-enabled physics
ACSW Frontiers '05 Proceedings of the 2005 Australasian workshop on Grid computing and e-research - Volume 44
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In silico (on the computer) oncology is a multi-disciplinary field that focuses on the examination and modeling of biological mechanisms related to the phenomenon of cancer. In silico oncology simulation model may be used for evaluating and comparing different therapeutic schemes while at the same time considering different values of critical parameters which present substantial inter-patient variability. As the number of the involved parameters and of the considered radiotherapeutic schemes increases, the resulting exponential increase in computational requirements makes the use of a grid environment for the execution of the simulations both a necessity for the involved researchers and an opportunity to make in silico oncology applications available to a wider biomedical and research community. In this paper, we describe a toolkit that enables the execution of in silico oncology simulations on grid infrastructures. This toolkit is designed and developed as a web portal with advanced features that facilitates the execution of in silico oncology simulations in grid environments. Several scenarios of radiotherapy simulations have been performed on the EGEE grid and indicative simulation results, as well as execution times are presented.