Modelling of Magnetic Resonance Spectra Using Mixtures for Binned and Truncated Data

  • Authors:
  • Juan M. Garcia-Gomez;Montserrat Robles;Sabine Huffel;Alfons Juan-Císcar

  • Affiliations:
  • BET-IBM, Polytechnical University of Valencia,;BET-IBM, Polytechnical University of Valencia,;Katholieke Universiteit Leuven, Dept. of Electrical Engineering, ESAT-SCD(SISTA),;DSIC, Polytechnical University of Valencia,

  • Venue:
  • IbPRIA '07 Proceedings of the 3rd Iberian conference on Pattern Recognition and Image Analysis, Part II
  • Year:
  • 2007

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Abstract

Magnetic Resonance Spectroscopy (MRS) provides the biochemical composition of a tissue under study. This information is useful for the in-vivo diagnosis of brain tumours. Prior knowledge of the relative position of the organic compound contributions in the MRS suggests the development of a probabilistic mixture model and its EM-based Maximum Likelihood Estimation for binned and truncated data. Experiments for characterizing and classifying Short Time Echo (STE) spectra from brain tumours are reported.