Adaptation in natural and artificial systems
Adaptation in natural and artificial systems
Programs for Digital Signal Processing
Programs for Digital Signal Processing
Application of the GA/KNN method to SELDI proteomics data
Bioinformatics
Find Key m/z Values in Predication of Mass Spectrometry Cancer Data
ICIC '08 Proceedings of the 4th international conference on Intelligent Computing: Advanced Intelligent Computing Theories and Applications - with Aspects of Theoretical and Methodological Issues
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In this paper wavelet analysis and Genetic Algorithm (GA) are performed to extract features and reduce dimensionality of mass spectrometry data. A set of wavelet features, which include detail coefficients and approximation coefficients, are extracted from mass spectrometry data. Detail coefficients are used to characterize the localized change of mass spectrometry data and approximation coefficients are used to compress mass spectrometry data, reducing the dimensionality. GA performs the further dimensionality reduction and optimizes the wavelet features. Experiments prove that this hybrid method of feature extraction is efficient way to characterize mass spectrometry data.