A framework for knowledge-based temporal abstraction
Artificial Intelligence
Discovery of Frequent Episodes in Event Sequences
Data Mining and Knowledge Discovery
Mining Sequential Patterns: Generalizations and Performance Improvements
EDBT '96 Proceedings of the 5th International Conference on Extending Database Technology: Advances in Database Technology
Fast Algorithms for Mining Association Rules in Large Databases
VLDB '94 Proceedings of the 20th International Conference on Very Large Data Bases
Regression Modeling Strategies
Regression Modeling Strategies
Discovery and inclusion of SOFA score episodes in mortality prediction
Journal of Biomedical Informatics
Temporal data mining for the quality assessment of hemodialysis services
Artificial Intelligence in Medicine
Mortality assessment in intensive care units via adverse events using artificial neural networks
Artificial Intelligence in Medicine
Integrating classification trees with local logistic regression in Intensive Care prognosis
Artificial Intelligence in Medicine
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Current predictive models in the intensive care rely on summaries of data collected at patient admission. It has been shown recently that temporal patterns of the daily Sequential Organ Failure Assessment (SOFA) scores can improve predictions. However, the derangement of the six individual organ systems underlying the calculation of a SOFA score were not taken into account, thus impeding the understanding of their prognostic merits. In this paper we propose a method for model induction that integrates in a novel way the individual organ failure scores with SOFA scores. The integration of these two correlated components is achieved by summarizing the historic SOFA information and at the same time by capturing the evolution of individual organ system failure status. The method also explicitly avoids the collinearity problem among organ failure episodes. We report on the application of our method to a large dataset and demonstrate its added value. The ubiquity of severity scores and sub-scores in medicine renders our approach relevant to a wide range of medical domains.