Machine Learning
The identification of dynamic gene-protein networks
KDECB'06 Proceedings of the 1st international conference on Knowledge discovery and emergent complexity in bioinformatics
On sparse representations in arbitrary redundant bases
IEEE Transactions on Information Theory
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In this paper we study the identification of sparse interaction networks as a machine learning problem. Sparsity mean that we are provided with a small data set and a high number of unknown components of the system, most of which are zero. Under these circumstances, a model needs to be learned that fits the underlying system, capable of generalization. This corresponds to the student-teacher setting in machine learning. In the first part of this paper we introduce a learning algorithm, based on L1-minimization, to identify interaction networks from poor data and analyze its dynamics with respect to phase transitions. The efficiency of the algorithm is measured by the generalization error, which represents the probability that the student is a good fit to the teacher. In the second part of this paper we show that from a system with a specific system size value the generalization error of other system sizes can be estimated. A comparison with a set of simulation experiments show a very good fit.