Journal of the ACM (JACM)
Information Processing Letters
Efficient Detection of Network Motifs
IEEE/ACM Transactions on Computational Biology and Bioinformatics (TCBB)
Fourier meets möbius: fast subset convolution
Proceedings of the thirty-ninth annual ACM symposium on Theory of computing
Bioinformatics
QNet: a tool for querying protein interaction networks
RECOMB'07 Proceedings of the 11th annual international conference on Research in computational molecular biology
Reaction motifs in metabolic networks
WABI'05 Proceedings of the 5th International conference on Algorithms in Bioinformatics
Sharp tractability borderlines for finding connected motifs in vertex-colored graphs
ICALP'07 Proceedings of the 34th international conference on Automata, Languages and Programming
Parameterized Complexity
Topology-Free Querying of Protein Interaction Networks
RECOMB 2'09 Proceedings of the 13th Annual International Conference on Research in Computational Molecular Biology
Maximum Motif Problem in Vertex-Colored Graphs
CPM '09 Proceedings of the 20th Annual Symposium on Combinatorial Pattern Matching
Finding and counting vertex-colored subtrees
MFCS'10 Proceedings of the 35th international conference on Mathematical foundations of computer science
Querying Graphs in Protein-Protein Interactions Networks Using Feedback Vertex Set
IEEE/ACM Transactions on Computational Biology and Bioinformatics (TCBB)
Complexity issues in vertex-colored graph pattern matching
Journal of Discrete Algorithms
Upper and lower bounds for finding connected motifs in vertex-colored graphs
Journal of Computer and System Sciences
Finding approximate and constrained motifs in graphs
CPM'11 Proceedings of the 22nd annual conference on Combinatorial pattern matching
Comparative analysis of protein networks: hard problems, practical solutions
Communications of the ACM
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We study the NP-complete Graph Motifproblem: given a vertex-colored graph G= (V,E) and a multiset Mof colors, does there exist an S茂戮驴 Vsuch that G[S] is connected and carries exactly (also with respect to multiplicity) the colors in M? We present an improved randomized algorithm for Graph Motifwith running time O(4.32|M|·|M|2·|E|). We extend our algorithm to list-colored graph vertices and the case where the motif G[S] needs not be connected. By way of contrast, we show that extending the request for motif connectedness to the somewhat "more robust" motif demands of biconnectedness or bridge-connectedness leads to W[1]-complete problems. Actually, we show that the presumably simpler problems of finding (uncolored) biconnected or bridge-connected subgraphs are W[1]-complete with respect to the subgraph size. Answering an open question from the literature, we further show that the parameter "number of connected motif components" leads to W[1]-hardness even when restricted to graphs that are paths.