Distributed Systems and Automated Biodiversity Informatics: Genomic Analysis and Geographic Visualization of Disease Evolution

Authors:
Andrew W. Hill;Robert P. Guralnick
Affiliations:
Department of Ecology and Evolutionary Biology, University of Colorado, Boulder, United States of America;Department of Ecology and Evolutionary Biology, University of Colorado, Boulder, United States of America and University of Colorado Museum, University of Colorado, Boulder, United States of Ameri ...
Venue:
BNCOD '08 Proceedings of the 25th British national conference on Databases: Sharing Data, Information and Knowledge
Year:
2008

Citing 3
Cited 0

Biodiversity Informatics Infrastructure: An Information Commons for the Biodiversity Community

VLDB '00 Proceedings of the 26th International Conference on Very Large Data Bases
HyPhy: hypothesis testing using phylogenies

Bioinformatics
RAxML-VI-HPC: maximum likelihood-based phylogenetic analyses with thousands of taxa and mixed models

Bioinformatics

Quantified Score

Hi-index	0.00

Visualization

Abstract

A core mission in biodiversity informatics is to build a computing infrastructure for rapid, real-time analysis of biodiversity information. We have created the information technology to mine, analyze, interpret and visualize how diseases are evolving across the globe. The system rapidly collects the newest and most complete data on dangerous strains of viruses that are able to infect human and animal populations. Following completion, the system will also test whether positions in the genome are under positive selection or purifying selection, a useful feature to monitor functional genomic charac-teristics such as, drug resistance, host specificity, and transmissibility. Our system's persistent monitoring and reporting of the distribution of dangerous and novel viral strains will allow for better threat forecasting. This information system allows for greatly increased efficiency in tracking the evolution of disease threats.