An Improved Multi-task Learning Approach with Applications in Medical Diagnosis

  • Authors:
  • Jinbo Bi;Tao Xiong;Shipeng Yu;Murat Dundar;R. Bharat Rao

  • Affiliations:
  • CAD and Knowledge Solutions, Siemens Medical Solutions, Malvern, USA PA 19355;Risk Management, Applied Research, eBay Inc., San Jose, USA CA 95125;CAD and Knowledge Solutions, Siemens Medical Solutions, Malvern, USA PA 19355;CAD and Knowledge Solutions, Siemens Medical Solutions, Malvern, USA PA 19355;CAD and Knowledge Solutions, Siemens Medical Solutions, Malvern, USA PA 19355

  • Venue:
  • ECML PKDD '08 Proceedings of the 2008 European Conference on Machine Learning and Knowledge Discovery in Databases - Part I
  • Year:
  • 2008

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Abstract

We propose a family of multi-task learning algorithms for collaborative computer aided diagnosis which aims to diagnose multiple clinically-related abnormal structures from medical images. Our formulations eliminate features irrelevant to all tasks, and identify discriminative features for each of the tasks. A probabilistic model is derived to justify the proposed learning formulations. By equivalence proof, some existing regularization-based methods can also be interpreted by our probabilistic model as imposing a Wishart hyperprior. Convergence analysis highlights the conditions under which the formulations achieve convexity and global convergence. Two real-world medical problems: lung cancer prognosis and heart wall motion analysis, are used to validate the proposed algorithms.