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Non-invasive physiological monitors are important subsystems of intensive care informatic systems. New innovative information methods and technology are presented for non-invasive human brain volumetric pulse wave physiological monitoring. Experimental study of a new, non-invasive ultrasonic intracranial pulse wave monitoring technology show the reactions of non-invasively recorded intracranial blood volume pulse waves (IBVPW) on healthy volunteers in different human body positions. A group of 13 healthy volunteers was studied. Body posture caused IBVPW, subwaves changes, ΔP2 = 18% and ΔP3 = 11%. The value of the IBVPW amplitude's ratio in supine and upright positions was 1.55 ± 0.61.