An Atlas-Based Segmentation Propagation Framework Using Locally Affine Registration --- Application to Automatic Whole Heart Segmentation

  • Authors:
  • Xiahai Zhuang;Kawal Rhode;Simon Arridge;Reza Razavi;Derek Hill;David Hawkes;Sebastien Ourselin

  • Affiliations:
  • Centre for Medical Image Computing, Med Phys Dept, UCL, UK WC1E 6BT;Interdisciplinary Medical Imaging Group, St Thomas' Hospital, KCL, UK SE1 7EH;Centre for Medical Image Computing, Med Phys Dept, UCL, UK WC1E 6BT;Interdisciplinary Medical Imaging Group, St Thomas' Hospital, KCL, UK SE1 7EH;Centre for Medical Image Computing, Med Phys Dept, UCL, UK WC1E 6BT;Centre for Medical Image Computing, Med Phys Dept, UCL, UK WC1E 6BT;Centre for Medical Image Computing, Med Phys Dept, UCL, UK WC1E 6BT

  • Venue:
  • MICCAI '08 Proceedings of the 11th International Conference on Medical Image Computing and Computer-Assisted Intervention, Part II
  • Year:
  • 2008

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Abstract

In this paper, we present a novel registration algorithm for locally affine registrations. This method preserves the anatomical and intensity class relationships between the local regions. A regularisation procedure is used to maintain a global diffeomorphic transformation. Combined with a novel generic method for accurately inverting the final deformation field, we include our techniques within an atlas-based segmentation propagation framework. We applied our method to automatically segment the whole heart from cardiac magnetic resonance images from a cohort of 18 volunteers (acquisition resolution 2 × 2 × 2 mm). The results show that the proposed method provides a robust initialisation for the atlas-based segmentation propagation framework refined with a fluid registration. We validated our approach against other registration strategies, and demonstrated that we improved the accuracy of the whole heart segmentations (1.8 ± 0.42 mm).