Mathematical and computer modeling of physiological systems
Mathematical and computer modeling of physiological systems
The SCIRun computational steering software system
Modern software tools for scientific computing
JDBC API Tutorial and Reference, Second Edition: Universal Data Access for the Java 2 Platform
JDBC API Tutorial and Reference, Second Edition: Universal Data Access for the Java 2 Platform
Engineering high-performance legacy codes as CORBA components for problem-solving environments
Journal of Parallel and Distributed Computing
A reference ontology for biomedical informatics: the foundational model of anatomy
Journal of Biomedical Informatics - Special issue: Unified medical language system
The HotBox: a visual user interface to medical data
Information Visualization - Special issue on visual analysis of human dynamics
Integrative computational frameworks for multiscale digital human modeling and simulation
ICCS'06 Proceedings of the 6th international conference on Computational Science - Volume Part IV
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Interest in complex integrated digital or virtual human modeling has seen a significant increase over the last decade. Coincident with that increased interest, Oak Ridge National Laboratory (ORNL) initiated the development of a human simulation tool, the Virtual Human. The Virtual Human includes a problem-solving environment (PSE) for implementing the integration of physiological models in different programming languages and connecting physiological function to anatomy. The Virtual Human PSE (VHPSE) provides the computational framework with which to develop the concept of a "Virtual Human." Supporting the framework is a data definition for modeling parameters, PhysioML, a Virtual Human Database (VHDB), and a Web-based graphical user interface (GUI) developed using Java. Following description of the VHPSE, we discuss four example implementations of models within the framework. Further expansion of a human modeling environment was carried out in the Defense Advanced Research Projects Agency Virtual Soldier Project. SCIRun served as the Virtual Soldier problem solving environment (VSPSE). We review and compare specific developments in these projects that have significant potential for the future of Virtual Human modeling and simulation. We conclude with an evaluation of areas of future work that will provide important extensions to the VHPSE and VSPSE and make possible a fully-integrated environment for human anatomical and physiological modeling: the Virtual Human.