Introduction to Computational Genomics: A Case Studies Approach
Introduction to Computational Genomics: A Case Studies Approach
CISIM '08 Proceedings of the 2008 7th Computer Information Systems and Industrial Management Applications
CISIM '08 Proceedings of the 2008 7th Computer Information Systems and Industrial Management Applications
Outliers in biometrical data: What's old, What's new
International Journal of Biometrics
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The genetic code of living organisms is inscribed into so called Open Reading Frames (ORFs) positioned in chromosomes. The code uses 20 amino acids as building blocks for the inscribed information. We show that the number of appearances of a given amino acid in ORFs on a yeast chromosome may be described in a highly satisfactory manner by the Negative Binomial (NB) distribution. The fit is surprisingly good. We show the results for ORFs found in four yeast chromosomes, namely no. 4, 7, 11 and 13. The negative binomial fit is shown (1) graphically; (2) considering the Kolmogorov statistic; (3) performing a chi-square test and (4) using simulated samples. The applicability of the Kolmogorov test to the analysed data is discussed.