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This paper presents a way to develop a game using an artificial chemistry. An artificial chemistry is an abstract model of chemical system. It is used in the research field of artificial life. We develop a roguelike game using an artificial chemistry with a specific approach, which we propose in this paper: first, we build a system to simulate the world of a roguelike game; then we remove a part of the system to make it a game. A small set of rules in the artificial chemistry is able to define the simulation, and removing a rule makes it a game. This shows the effectiveness of the present approach in developing a certain type of game using the artificial chemistry.