Graph spectra as a systematic tool in computational biology

  • Authors:
  • Anirban Banerjee;Jürgen Jost

  • Affiliations:
  • Max Planck Institute for Mathematics in the Sciences, Inselstreet 22, 04103 Leipzig, Germany;Max Planck Institute for Mathematics in the Sciences, Inselstreet 22, 04103 Leipzig, Germany

  • Venue:
  • Discrete Applied Mathematics
  • Year:
  • 2009

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Abstract

We present the spectrum of the (normalized) graph Laplacian as a systematic tool for the investigation of networks, and we describe basic properties of eigenvalues and eigenfunctions. Processes of graph formation like motif joining or duplication leave characteristic traces in the spectrum. This can suggest hypotheses about the evolution of a graph representing biological data.