Retarded differential equations
Journal of Computational and Applied Mathematics - Special issue on numerical anaylsis 2000 Vol. VI: Ordinary differential equations and integral equations
Computational approaches to parameter estimation and model selection in immunology
Journal of Computational and Applied Mathematics - Special issue: Mathematics applied to immunology
Adjoint equations and analysis of complex systems: application to virus infection modelling
Journal of Computational and Applied Mathematics - Special issue: Mathematics applied to immunology
Discontinuous solutions of neutral delay differential equations
Applied Numerical Mathematics - The third international conference on the numerical solutions of volterra and delay equations, May 2004, Tempe, AZ
Sense from sensitivity and variation of parameters
Applied Numerical Mathematics - The third international conference on the numerical solutions of volterra and delay equations, May 2004, Tempe, AZ
Applied Numerical Mathematics - Tenth seminar on and differential-algebraic equations (NUMDIFF-10)
Rival approaches to mathematical modelling in immunology
Journal of Computational and Applied Mathematics
Mathematics and Computers in Simulation
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The problem that motivates the considerations here is the construction of mathematical models of natural phenomena that depend upon past states. The paper divides naturally into two parts: in the first, we expound the inter-connection between ordinary differential equations, delay-differential equations, neutral delay-differential equations and integral equations (with emphasis on certain linear cases). As we show, this leads to a natural hierarchy of model complexity when such equations are used in mathematical and computational modelling, and to the possibility of reformulating problems either to facilitate their numerical solution or to provide mathematical insight, or both. Volterra integral equations include as special cases the others we consider. In the second part, we develop some practical and theoretical consequences of results given in the first part. In particular, we consider various approaches to the definition of an adjoint, we establish (notably, in the context of sensitivity analysis for neutral delay-differential equations) roles for well-defined adjoints and 'quasi-adjoints', and we explore relationships between sensitivity analysis, the variation of parameters formulae, the fundamental solution and adjoints.