Probabilistic Networks and Expert Systems
Probabilistic Networks and Expert Systems
The Influence of Influence Diagrams in Medicine
Decision Analysis
Journal of Biomedical Informatics
Bayesian Networks and Decision Graphs
Bayesian Networks and Decision Graphs
Artificial Intelligence in Medicine
Editorial: Bayesian networks in biomedicine and health-care
Artificial Intelligence in Medicine
Formal-Transfer In and Out of Stroke Care Units: An Analysis Using Bayesian Networks
International Journal of Healthcare Information Systems and Informatics
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Objective: The prognosis of cancer patients treated with intensity-modulated radiation-therapy (IMRT) is inherently uncertain, depends on many decision variables, and requires that a physician balance competing objectives: maximum tumor control with minimal treatment complications. Methods: In order to better deal with the complex and multiple objective nature of the problem we have combined a prognostic probabilistic model with multi-attribute decision theory which incorporates patient preferences for outcomes. Results: The response to IMRT for prostate cancer was modeled. A Bayesian network was used for prognosis for each treatment plan. Prognoses included predicting local tumor control, regional spread, distant metastases, and normal tissue complications resulting from treatment. A Markov model was constructed and used to calculate a quality-adjusted life-expectancy which aids in the multi-attribute decision process. Conclusions: Our method makes explicit the tradeoffs patients face between quality and quantity of life. This approach has advantages over current approaches because with our approach risks of health outcomes and patient preferences determine treatment decisions.