Cancer classification using microarray and layered architecture genetic programming
Proceedings of the 11th Annual Conference Companion on Genetic and Evolutionary Computation Conference: Late Breaking Papers
ACSC '12 Proceedings of the Thirty-fifth Australasian Computer Science Conference - Volume 122
Hybridising harmony search with a Markov blanket for gene selection problems
Information Sciences: an International Journal
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In this work we compare the use of a Particle Swarm Optimization (PSO) and a Genetic Algorithm (GA) (both augmented with Support Vector Machines SVM) for the classification of high dimensional Microarray Data. Both algorithms are used for finding small samples of informative genes amongst thousands of them. A SVM classifier with 10-fold cross-validation is applied in order to validate and evaluate the provided solutions. A first contribution is to prove that PSOSVM is able to find interesting genes and to provide classification competitive performance. Specifically, a new version of PSO, called Geometric PSO, is empirically evaluated for the first time in this work. In this sense, a comparison of this approach with a new GASV M and also with other existing methods of literature is provided. A second important contribution consists in the actual discovery of new and challenging results on six public datasets identifying significant in the development of a variety of cancers (leukemia, breast, colon, ovarian, prostate, and lung).