On the Reachability of Trustworthy Information from Integrated Exploratory Biological Queries
DILS '09 Proceedings of the 6th International Workshop on Data Integration in the Life Sciences
Believe it or not: adding belief annotations to databases
Proceedings of the VLDB Endowment
Evaluation of probabilistic and logical inference for a SNP annotation system
Journal of Biomedical Informatics
Tractability in probabilistic databases
Proceedings of the 14th International Conference on Database Theory
Oblivious bounds on the probability of boolean functions
ACM Transactions on Database Systems (TODS)
Reducing uncertainty of schema matching via crowdsourcing
Proceedings of the VLDB Endowment
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Mediator-based data integration systems resolve exploratory queries by joining data elements across sources. In the presence of uncertainties, such multiple expansions can quickly lead to spurious connections and incorrect results. The BioRank project investigates formalisms for modeling uncertainty during scientific data integration and for ranking uncertain query results. Our motivating application is protein function prediction. In this paper we show that: (i) explicit modeling of uncertainties as probabilities increases our ability to predict less-known or previously unknown functions (though it does not improve predicting the well-known). This suggests that probabilistic uncertainty models offer utility for scientific knowledge discovery; (ii) small perturbations in the input probabilities tend to produce only minor changes in the quality of our result rankings. This suggests that our methods are robust against slight variations in the way uncertainties are transformed into probabilities; and (iii) several techniques allow us to evaluate our probabilistic rankings efficiently. This suggests that probabilistic query evaluation is not as hard for real-world problems as theory indicates.