Rec-I-DCM3: A Fast Algorithmic Technique for Reconstructing Large Phylogenetic Trees
CSB '04 Proceedings of the 2004 IEEE Computational Systems Bioinformatics Conference
Large Grain Size Stochastic Optimization Alignment
BIBE '06 Proceedings of the Sixth IEEE Symposium on BionInformatics and BioEngineering
Maximum likelihood of evolutionary trees is hard
RECOMB'05 Proceedings of the 9th Annual international conference on Research in Computational Molecular Biology
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PSODA is a comprehensive phylogenetics package, including alignment, phylogenetic search under both parsimony and maximum likelihood, and visualisation and analysis tools. PSODA offers performance comparable to PAUP* in an open source package that aims to provide a foundation for researchers examining new phylogenetic algorithms. A key new feature is PsodaScript, an extension to the nearly ubiquitous NEXUS format, that includes conditional and loop constructs; thereby allowing complex meta-search techniques like the parsimony ratchet to be easily and compactly implemented. PSODA promises to be a valuable tool in the future development of novel phylogenetic techniques. This paper seeks to familiarise researchers with PSODA and its features, in particular the internal scripting language, PsodaScript. PSODA is freely available from the PSODA.