On spectral numerical characterizations of DNA sequences based on Hamori curve representation

  • Authors:

  • Igor Pesek;Janez Žerovnik

  • Affiliations:

  • Institute of mathematics physics and mechanics, Ljubljana, Slovenia;Institute of mathematics physics and mechanics, Ljubljana, Slovenia and University of Ljubljana, Faculty of Mechanical Engineering, Ljubljana, Slovenia

  • Venue:
  • MCBC'09 Proceedings of the 10th WSEAS international conference on Mathematics and computers in biology and chemistry
  • Year:
  • 2009

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Abstract

We present new numerical characterization of DNA sequences that is based on the modified graphical representation proposed by Hamori. While Hamori embeds the sequence into Euclidean space, we use analogous embedding into the strong product of graphs, K4 ??? Pn, with weighted edges. Based on this representation, a novel numerical characterization was proposed in [Pesek and Žerovnik, MATCH Commun. Math. Comput. Chem. (Krag.), vol 60, 2008, 301-312] which is based on the products of ten eigenvalues from the start and the end of the descending ordered list of the eigenvalues of the L/L matrices associated with DNA. In this paper we compare two further numerical characterizations of the same type emphasizing the robustness of the approach.