An Improved Binary Particle Swarm Optimisation for Gene Selection in Classifying Cancer Classes

Authors:
Mohd Saberi Mohamad;Sigeru Omatu;Safaai Deris;Michifumi Yoshioka;Anazida Zainal
Affiliations:
Department of Computer Science and Intelligent Systems, Graduate School of Engineering, Osaka Prefecture University, Sakai, Osaka, Japan 599-8531 and Department of Software Engineering, Faculty of ...;Department of Computer Science and Intelligent Systems, Graduate School of Engineering, Osaka Prefecture University, Sakai, Osaka, Japan 599-8531;Department of Software Engineering, Faculty of Computer Science and Information Systems, Universiti Teknologi Malaysia, Skudai, Malaysia 81310;Department of Computer Science and Intelligent Systems, Graduate School of Engineering, Osaka Prefecture University, Sakai, Osaka, Japan 599-8531;Department of Software Engineering, Faculty of Computer Science and Information Systems, Universiti Teknologi Malaysia, Skudai, Malaysia 81310
Venue:
IWANN '09 Proceedings of the 10th International Work-Conference on Artificial Neural Networks: Part II: Distributed Computing, Artificial Intelligence, Bioinformatics, Soft Computing, and Ambient Assisted Living
Year:
2009

Citing 3
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Abstract

The application of microarray data for cancer classification has recently gained in popularity. The main problem that needs to be addressed is the selection of a smaller subset of genes from the thousands of genes in the data that contributes to a disease. This selection process is difficult because of the availability of the small number of samples compared to the huge number of genes, many irrelevant genes, and noisy genes. Therefore, this paper proposes an improved binary particle swarm optimisation to select a near-optimal (smaller) subset of informative genes that is relevant for cancer classification. Experimental results show that the performance of the proposed method is superior to a standard version of particle swarm optimisation and other related previous works in terms of classification accuracy and the number of selected genes.