Partitional Clustering of Protein Sequences --- An Inductive Logic Programming Approach

Authors:
Nuno A. Fonseca;Vitor Santos Costa;Rui Camacho;Cristina Vieira;Jorge Vieira
Affiliations:
Instituto de Biologia Molecular e Celular (IBMC), Universidade do Porto, Porto, Portugal 4150-180 and CRACS-INESC Porto LA, Universidade do Porto, Porto, Portugal 4169-007;CRACS-INESC Porto LA, Universidade do Porto, Porto, Portugal 4169-007;LIAAD-INESC Porto LA & FEUP, Universidade do Porto, Porto, Portugal 4200-465;Instituto de Biologia Molecular e Celular (IBMC), Universidade do Porto, Porto, Portugal 4150-180;Instituto de Biologia Molecular e Celular (IBMC), Universidade do Porto, Porto, Portugal 4150-180
Venue:
IWANN '09 Proceedings of the 10th International Work-Conference on Artificial Neural Networks: Part II: Distributed Computing, Artificial Intelligence, Bioinformatics, Soft Computing, and Ambient Assisted Living
Year:
2009

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Abstract

We present a novel approach to cluster sets of protein sequences, based on Inductive Logic Programming (ILP). Preliminary results show that the method proposed produces understandable descriptions/explanations of the clusters. Furthermore, it can be used as a knowledge elicitation tool to explain clusters proposed by other clustering approaches, such as standard phylogenetic programs.