Development of a Workflow for Protein Sequence Analysis Based on the Taverna Workbench® Software

  • Authors:

  • Mariana B. Monteiro;Manuela E. Pintado;Francisco X. Malcata;Conrad Bessant;Patrícia R. Moreira

  • Affiliations:

  • Integromics, S.L., Tres Cantos, Madrid, Spain 28760;CBQF, Escola Superior de Biotecnologia, Universidade Católica Portuguesa, R. Dr. António Bernardino de Almeida, Porto, Porto, Portugal P-4200-072;CBQF, Escola Superior de Biotecnologia, Universidade Católica Portuguesa, R. Dr. António Bernardino de Almeida, Porto, Porto, Portugal P-4200-072;Cranfield Health, Cranfield University, Bedfordshire, England, United Kingdom MK43 0AL;CBQF, Escola Superior de Biotecnologia, Universidade Católica Portuguesa, R. Dr. António Bernardino de Almeida, Porto, Porto, Portugal P-4200-072

  • Venue:
  • IWANN '09 Proceedings of the 10th International Work-Conference on Artificial Neural Networks: Part II: Distributed Computing, Artificial Intelligence, Bioinformatics, Soft Computing, and Ambient Assisted Living
  • Year:
  • 2009

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Abstract

A workflow based on the Taverna Workbench® software and tentatively named WPSA was developed to perform a generic protein sequence analysis eliminating the need to cut and paste data throughout web applications. The program performs a homology search, a multiple sequence alignment and a phylogeny analysis using PHYLogeny Interface Package (PHYLIP). The workflow designed gives a fast and significant answer to the user about the input sequence entered taking between 5 to 10 minutes to run depending on the Internet connection and web services.