ZARAMIT: A System for the Evolutionary Study of Human Mitochondrial DNA

Authors:
Roberto Blanco;Elvira Mayordomo
Affiliations:
Departamento de Informática e Ingeniería de Sistemas Instituto de Investigación en Ingeniería de Aragón (I3A), Universidad de Zaragoza. María de Luna 1, Zaragoza, Spa ...;Departamento de Informática e Ingeniería de Sistemas Instituto de Investigación en Ingeniería de Aragón (I3A), Universidad de Zaragoza. María de Luna 1, Zaragoza, Spa ...
Venue:
IWANN '09 Proceedings of the 10th International Work-Conference on Artificial Neural Networks: Part II: Distributed Computing, Artificial Intelligence, Bioinformatics, Soft Computing, and Ambient Assisted Living
Year:
2009

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Abstract

ZARAMIT is an information system capable of fully automated phylogeny reconstruction. Methods have been tailored to mitochondrial DNA sequences, with focus on subproblem partitioning. We have built exhaustive human mitochondrial phylogenies (approximately 5500 sequences) and detected problems in existing haplogroup hierarchies through data-driven classification. Information on the project can be found on zaramit.org .