DNA Library Screening, Pooling Design and Unitary Spaces

Authors:
Suogang Gao;Zengti Li;Jiangchen Yu;Xiaofeng Gao;Weili Wu
Affiliations:
Mathematics and Information College, Hebei Normal University, Shijiazhuang, China 050016;Mathematics and Information College, Langfang Normal College, Langfang, China 065000;Department of Computer Science, University of Texas at Dallas, Richardson, USA 75080;Department of Computer Science, University of Texas at Dallas, Richardson, USA 75080;Department of Computer Science, University of Texas at Dallas, Richardson, USA 75080
Venue:
COCOA '09 Proceedings of the 3rd International Conference on Combinatorial Optimization and Applications
Year:
2009

Citing 3
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A simple construction of d-disjunct matrices with certain constant weights

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New constructions of non-adaptive and error-tolerance pooling designs

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Two constructions of new error-correcting pooling designs from orthogonal spaces over a finite field of characteristic 2

Journal of Combinatorial Optimization

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Abstract

Pooling design is an important research topic in bio- informatics due to its wide applications in molecular biology, especially DNA library screening. In this paper, with unitary spaces over finite fields, we present two new constructions whose efficiency ratio, i.e., the ratio between the number of tests and the number of items, is smaller than some of existing construction.