Folding@home: Lessons from eight years of volunteer distributed computing

Authors:
Adam L. Beberg;Daniel L. Ensign;Guha Jayachandran;Siraj Khaliq;Vijay S. Pande
Affiliations:
Computer Science Dept, Stanford University, USA;Chemistry Department, Stanford University, USA;Computer Science Dept, Stanford University, USA;Computer Science Dept, Stanford University, USA;Chemistry Department, Stanford University, USA
Venue:
IPDPS '09 Proceedings of the 2009 IEEE International Symposium on Parallel&Distributed Processing
Year:
2009

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Abstract

Accurate simulation of biophysical processes requires vast computing resources. Folding@home is a distributed computing system first released in 2000 to provide such resources needed to simulate protein folding and other biomolecular phenomena. Now operating in the range of 5 PetaFLOPS sustained, it provides more computing power than can typically be gathered and operated locally due to cost, physical space, and electrical/cooling load. This paper describes the architecture and operation of Folding@home, along with some lessons learned over the lifetime of the project.