Assessing the Eligibility of Kidney Transplant Donors

  • Authors:
  • Francisco Reinaldo;Carlos Fernandes;Md. Anishur Rahman;Andreia Malucelli;Rui Camacho

  • Affiliations:
  • FEUP, Universidade do Porto, Rua Dr. Roberto Frias, sn, 4200-465 Porto, Portugal, and, UnilesteMG - Centro Universitário do Leste de Minas Gerais, GIC - Grupo de Inteligência Computacion ...;Pontifical Catholic University of Paraná - PUCPR, PostGraduate Programme in Health Technology - PPGTS, Curitiba, Brazil 215-901;FEUP, Universidade do Porto, Porto, Portugal 4200-465;Pontifical Catholic University of Paraná - PUCPR, PostGraduate Programme in Health Technology - PPGTS, Curitiba, Brazil 80215-901;FEUP, Universidade do Porto, Porto, Portugal 4200-465

  • Venue:
  • MLDM '09 Proceedings of the 6th International Conference on Machine Learning and Data Mining in Pattern Recognition
  • Year:
  • 2009

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Abstract

Organ transplantation is a highly complex decision process that requires expert decisions. The major problem in a transplantation procedure is the possibility of the receiver's immune system attack and destroy the transplanted tissue. It is therefore of capital importance to find a donor with the highest possible compatibility with the receiver, and thus reduce rejection. Finding a good donor is not a straightforward task because a complex network of relations exists between the immunological and the clinical variables that influence the receiver's acceptance of the transplanted organ. Currently the process of analyzing these variables involves a careful study by the clinical transplant team. The number and complexity of the relations between variables make the manual process very slow. In this paper we propose and compare two Machine Learning algorithms that might help the transplant team in improving and speeding up their decisions. We achieve that objective by analyzing past real cases and constructing models as set of rules. Such models are accurate and understandable by experts.