Oxygen saturation regularity analysis in the diagnosis of obstructive sleep apnea

  • Authors:

  • Félix del Campo;Roberto Hornero;Carlos Zamarrón;Daniel E. Abasolo;Daniel Álvarez

  • Affiliations:

  • Hospital del Río Hortega, Servicio de Neumología, C/Cardenal Torquemada s/n, 47010 Valladolid, Spain;ETSI-Telecomunicación University of Valladolid, Camino del Cementerio s/n, 47011 Valladolid, Spain;Hospital Clínico Universitario, Servicio de Neumología, C/Travesia de La Choupana s/n, 15706 Santiago de Compostela, Spain;ETSI-Telecomunicación University of Valladolid, Camino del Cementerio s/n, 47011 Valladolid, Spain;ETSI-Telecomunicación University of Valladolid, Camino del Cementerio s/n, 47011 Valladolid, Spain

  • Venue:
  • Artificial Intelligence in Medicine
  • Year:
  • 2006

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Abstract

Objective: The present study assessed the validity of approximate entropy (ApEn) analysis of arterial oxygen saturation (SaO"2) data obtained from pulse oximetric recordings as a diagnostic test for obstructive sleep apnea (OSA) in patients clinically suspected of suffering this disease. Methodology: A sample of 187 referred outpatients, clinically suspected of having OSA, was studied using nocturnal pulse oximetric recording performed simultaneously with complete polysomnography. ApEn analysis was applied to SaO"2 data. Results: Patients with OSA presented significantly higher approximate entropy levels than those without OSA (1.08+/-0.30 versus 0.47+/-0.26). Apnea-hypopnea index was correlated significantly with ApEn (r=0.607; p