Partial logistic artificial neural network for competing risks regularized with automatic relevance determination

  • Authors:
  • Paulo J. G. Lisboa;Terence A. Etchells;Ian H. Jarman;Corneliu T. C. Arsene;M. S. Hane Aung;Antonio Eleuteri;Azzam F. G. Taktak;Federico Ambrogi;Patrizia Boracchi;Elia Biganzoli

  • Affiliations:
  • School of Computing and Mathematical Sciences, Liverpool John Moores University, Liverpool, UK;School of Computing and Mathematical Sciences, Liverpool John Moores University, Liverpool, UK;School of Computing and Mathematical Sciences, Liverpool John Moores University, Liverpool, UK;School of Engineering Sciences, University of Southampton, Southampton, UK and School of Computing and Mathematical Sciences, Liverpool John Moores University, Liverpool, UK;Department of Electrical Engineering and Electronics, University of Liverpool, Liverpool, UK;Department of Medical Physics and Clinical Engineering, Royal Liverpool University Hospital, Liverpool, UK;Department of Medical Physics and Clinical Engineering, Royal Liverpool University Hospital, Liverpool, UK;Istituto Di Statistica Medica e Biometria, Università degli Studi Di Milano, Milan, Italy;Istituto Di Statistica Medica e Biometria, Università degli Studi Di Milano, Milan, Italy;Istituto Di Statistica Medica e Biometria, Università degli Studi Di Milano, Milan, Italy and Unita Operativa di Statistica Medica e Biometria, Instituto Nazionale per lo Studio e la Cura dei ...

  • Venue:
  • IEEE Transactions on Neural Networks
  • Year:
  • 2009

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Abstract

Time-to-event analysis is important in a wide range of applications from clinical prognosis to risk modeling for credit scoring and insurance. In risk modeling, it is sometimes required to make a simultaneous assessment of the hazard arising from two or more mutually exclusive factors. This paper applies to an existing neural network model for competing risks (PLANNCR), a Bayesian regularization with the standard approximation of the evidence to implement automatic relevance determination (PLANNCR-ARD). The theoretical framework for the model is described and its application is illustrated with reference to local and distal recurrence of breast cancer, using the data set of Veronesi et al. (1995).