On equation of arm gait of Huntington Disease patient

  • Authors:

  • O. Ibidapo-Obe;O. O. E. Ajibola;V. O. S. Olunloyo

  • Affiliations:

  • Faculty of Engineering, Department of Systems Engineering, University of Lagos, Akoka, Yaba, Lagos 234(01), Nigeria.;Faculty of Engineering, Department of Systems Engineering, University of Lagos, Akoka, Yaba, Lagos 234(01), Nigeria.;Faculty of Engineering, Department of Systems Engineering, University of Lagos, Akoka, Yaba, Lagos 234(01), Nigeria

  • Venue:
  • International Journal of Biometrics
  • Year:
  • 2010

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Abstract

Huntington's Disease (HD) is a progressive autosomal dominant trait, which usually begins in middle age; it is characterised by choreiform movements. The genetic defect that results in HD has been traced to an unstable expanded CAG trinucleotide repeat mutation in a novel gene on the short arm of chromosome 4. In this work, an attempt is made to promote a better understanding of the physiological chorea associated with human health hazard of HD origin by proposing a mathematical model which describes the arm gait of HD patient.