An automatic gene ontology software tool for bicluster and cluster comparisons

Authors:
Fadhl M. Al-Akwaa;Yasser M. Kadah
Affiliations:
University of Science and Technology, Sana'a, Yemen and Biomedical Engineering Department, Cairo University;Biomedical Engineering Department, Cairo University and Center for Informatics Science, Nile University, Egypt
Venue:
CIBCB'09 Proceedings of the 6th Annual IEEE conference on Computational Intelligence in Bioinformatics and Computational Biology
Year:
2009

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Abstract

We propose an Automatic Gene Ontology (AGO) software as a flexible, open-source Matlab software tool that allows the user to easily compare the results of the bicluster and cluster methods. This software provides several methods to differentiate and compare the results of candidate algorithms. The results reveal that bicluster/cluster algorithms could be considered as integrated modules to recover the interesting patterns in the microarray datasets. The further application of AGO could to solve the dimensionality reduction of the gene regulatory networks. Availability: AGO and help file is available at http://home.k-space.org/FADL/Downloads/AGO_prgram.zip