Statistical Location Model for Abdominal Organ Localization

  • Authors:
  • Jianhua Yao;Ronald M. Summers

  • Affiliations:
  • The National Institutes of Health, Imaging Biomarkers and Computer Aided Diagnosis Lab, Clinical Center, Bethesda, USA 20892;The National Institutes of Health, Imaging Biomarkers and Computer Aided Diagnosis Lab, Clinical Center, Bethesda, USA 20892

  • Venue:
  • MICCAI '09 Proceedings of the 12th International Conference on Medical Image Computing and Computer-Assisted Intervention: Part II
  • Year:
  • 2009

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Abstract

Initial placement of the models is an essential pre-processing step for model-based organ segmentation. Based on the observation that organs move along with the spine and their relative locations remain relatively stable, we built a statistical location model (SLM) and applied it to abdominal organ localization. The model is a point distribution model which learns the pattern of variability of organ locations relative to the spinal column from a training set of normal individuals. The localization is achieved in three stages: spine alignment, model optimization and location refinement. The SLM is optimized through maximum a posteriori estimation of a probabilistic density model constructed for each organ. Our model includes five organs: liver, left kidney, right kidney, spleen and pancreas. We validated our method on 12 abdominal CTs using leave-one-out experiments. The SLM enabled reduction in the overall localization error from 62.0±28.5 mm to 5.8±1.5 mm. Experiments showed that the SLM was robust to the reference model selection.