A limited memory algorithm for bound constrained optimization
SIAM Journal on Scientific Computing
ECG-gated interventional cardiac reconstruction for non- periodic motion
MICCAI'10 Proceedings of the 13th international conference on Medical image computing and computer-assisted intervention: Part I
Stochastic 3d motion compensation of coronary arteries from monoplane angiograms
MICCAI'12 Proceedings of the 15th international conference on Medical Image Computing and Computer-Assisted Intervention - Volume Part I
Pushing the limits for medical image reconstruction on recent standard multicore processors
International Journal of High Performance Computing Applications
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Anatomical and functional information of cardiac vasculature is a key component of future developments in the field of interventional cardiology. With the technology of C-arm CT it is possible to reconstruct intraprocedural 3-D images from angiographic projection data. Current approaches attempt to add the temporal dimension (4-D) by ECG-gating in order to distinct physical states of the heart. This model assumes that the heart motion is periodic. However, frequently arrhytmic heart signals are observed in a clinical environment. In addition breathing motion can still occur. We present a reconstruction method based on a 4-D time-continuous motion field which is parameterized by the acquisition time and not the quasi-periodic heart phase. The output of our method is twofold. It provides a motion compensated 3-D reconstruction (anatomic information) and a motion field (functional information). In a physical phantom experiment a vessel of size 3.08 mm undergoing a non-periodic motion was reconstructed. The resulting diameters were 3.42 mm and 1.85 mm assuming non-periodic and periodic motion, respectively. Further, for two clinical cases (coronary arteries and coronary sinus) it is demonstrated that the presented algorithm outperforms periodic approaches and is able to handle realistic irregular heart motion.