Estimating Continuous 4D Wall Motion of Cerebral Aneurysms from 3D Rotational Angiography

  • Authors:
  • Chong Zhang;Mathieu Craene;Maria-Cruz Villa-Uriol;Jose M. Pozo;Bart H. Bijnens;Alejandro F. Frangi

  • Affiliations:
  • Center for Computational Imaging & Simulation Technologies in Biomedicine (CISTIB), Universitat Pompeu Fabra, Barcelona, Spain and Networking Research Center on Bioengineering, Biomaterials and Na ...;Networking Research Center on Bioengineering, Biomaterials and Nanomedicine (CIBER-BBN), Spain and Center for Computational Imaging & Simulation Technologies in Biomedicine (CISTIB), Universitat P ...;Center for Computational Imaging & Simulation Technologies in Biomedicine (CISTIB), Universitat Pompeu Fabra, Barcelona, Spain and Networking Research Center on Bioengineering, Biomaterials and Na ...;Center for Computational Imaging & Simulation Technologies in Biomedicine (CISTIB), Universitat Pompeu Fabra, Barcelona, Spain and Networking Research Center on Bioengineering, Biomaterials and Na ...;Institució Catalana de Recerca i Estudis Avançats (ICREA), Barcelona, Spain and Center for Computational Imaging & Simulation Technologies in Biomedicine (CISTIB), Universitat Pompeu Fab ...;Center for Computational Imaging & Simulation Technologies in Biomedicine (CISTIB), Universitat Pompeu Fabra, Barcelona, Spain and Networking Research Center on Bioengineering, Biomaterials and Na ...

  • Venue:
  • MICCAI '09 Proceedings of the 12th International Conference on Medical Image Computing and Computer-Assisted Intervention: Part I
  • Year:
  • 2009

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Abstract

This paper presents a technique to recover dynamic 3D vascular morphology from a single 3D rotational X-ray angiography acquisition. The dynamic morphology corresponding to a canonical cardiac cycle is represented via a 4D B -spline based spatiotemporal deformation. Such deformation is estimated by simultaneously matching the forward projections of a sequence of the temporally deformed 3D reference volume to the entire 2D measured projection sequence. A joint use of two acceleration strategies is also proposed: semi-precomputation of forward projections and registration metric computation based on a narrow-band region-of-interest. Digital and physical phantoms of pulsating cerebral aneurysms have been used for evaluation. Accurate estimation has been obtained in recovering sub-voxel pulsation, even from images with substantial intensity inhomogeneity. Results also demonstrate that the acceleration strategies can reduce memory consumption and computational time without degrading the performance.