Task-Optimal Registration Cost Functions

  • Authors:
  • B. T. Yeo;Mert Sabuncu;Polina Golland;Bruce Fischl

  • Affiliations:
  • Computer Science and Artificial Intelligence Laboratory, MIT, USA;Computer Science and Artificial Intelligence Laboratory, MIT, USA;Computer Science and Artificial Intelligence Laboratory, MIT, USA;Athinoula A. Martinos Center for Biomedical Imaging, MGH/HMS, USA and Computer Science and Artificial Intelligence Laboratory, MIT, USA

  • Venue:
  • MICCAI '09 Proceedings of the 12th International Conference on Medical Image Computing and Computer-Assisted Intervention: Part I
  • Year:
  • 2009

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Abstract

In this paper, we propose a framework for learning the parameters of registration cost functions --- such as the tradeoff between the regularization and image similiarity term --- with respect to a specific task. Assuming the existence of labeled training data, we specialize the framework for the task of localizing hidden labels via image registration. We learn the parameters of the weighted sum of squared differences (wSSD) image similarity term that are optimal for the localization of Brodmann areas (BAs) in a new subject based on cortical geometry. We demonstrate state-of-the-art localization of V1, V2, BA44 and BA45.