NCI Thesaurus: A semantic model integrating cancer-related clinical and molecular information
Journal of Biomedical Informatics
OBO-Edit—an ontology editor for biologists
Bioinformatics
Ontology change: Classification and survey
The Knowledge Engineering Review
Analyzing the Evolution of Life Science Ontologies and Mappings
DILS '08 Proceedings of the 5th international workshop on Data Integration in the Life Sciences
Guest Editorial: Special Issue on Auditing of Terminologies
Journal of Biomedical Informatics
Discovering evolving regions in life science ontologies
DILS'10 Proceedings of the 7th international conference on Data integration in the life sciences
COnto-Diff: generation of complex evolution mappings for life science ontologies
Journal of Biomedical Informatics
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Ontologies have become very popular in life sciences and other domains. They mostly undergo continuous changes and new ontology versions are frequently released. However, current analysis studies do not consider the ontology changes reflected in different versions but typically limit themselves to a specific ontology version which may quickly become obsolete. To allow applications easy access to different ontology versions we propose a central and uniform management of the versions of different biomedical ontologies. The proposed database approach takes concept and structural changes of succeeding ontology versions into account thereby supporting different kinds of change analysis. Furthermore, it is very space-efficient by avoiding redundant storage of ontology components which remain unchanged in different versions. We evaluate the storage requirements and query performance of the proposed approach for the Gene Ontology.